Table 1.
Effects of heat shock on expression of selected genes involved in the heat shock protein response
| Gene symbol | Description | Expression level, control | Expression level, heat shock | Fold change | P |
|---|---|---|---|---|---|
|
HSPA1A |
Heat shock 70 kDa protein 1A |
3 |
6 |
2.11 |
0.063 |
|
HSPB11 |
Heat shock protein family B (small), member 11 |
26 |
53 |
2.0 |
0.027 |
|
HSPB1 |
Heat shock 27kDa protein 1 |
607 |
982 |
1.62 |
0.085 |
|
HSPH1 |
Heat shock 105 kDa/110kDa protein 1 |
924 |
1377 |
1.49 |
0.208 |
|
HSPBP1 |
heat shock 70kDa binding protein, cytoplasmic cochaperone 1 |
13 |
20 |
1.48 |
0.042 |
|
DNAJC28 |
DnaJ (Hsp40) homolog, subfamily C, member 28 |
9 |
12 |
1.30 |
0.513 |
|
HSP90AA1 |
Heat shock protein 90kDa alpha (cytosolic), class A member 1 |
38026 |
47565 |
1.25 |
0.439 |
|
HSPA8 |
heat shock 70kDa protein 8 (hsc70) |
2949 |
3583 |
1.21 |
0.471 |
|
HSP90AB1 |
Heat shock protein 90kDa alpha (cytosolic), class B member 1 |
1135 |
1359 |
1.2 |
0.359 |
|
HSPE1 |
Heat shock 10kDa protein 1 (chaperonin 10) |
57871 |
60682 |
1.05 |
0.796 |
|
HSPD1 |
heat shock 60kDa protein 1 (chaperonin) |
154 |
161 |
1.05 |
0.869 |
|
HSPB6 |
heat shock protein, alpha-crystallin-related, B6 |
12 |
12 |
1.00 |
1.00 |
|
HSF1 |
Heat shock factor protein 1 |
87 |
87 |
1.00 |
0.962 |
|
DNAJB12 |
DnaJ (Hsp40) homolog, subfamily B, member 12 |
22 |
18 |
0.83 |
0.053 |
|
DNAJC25 |
DnaJ (Hsp40) homolog, subfamily C , member 25 |
150 |
125 |
0.83 |
0.075 |
| HSF2 | Heat shock factor protein 2 | 65 | 48 | 0.73 | 0.444 |