Table 4. Area and size of liver tumors^a.

		Tumor Number (tumor/mouse)		Total Tumor Area (in mm3/per tumor bearing mouse)b		Tumor Size (in mm3/tumor per tumor bearing mouse)b
Genotype	Group	Adenomas	Carcinomas	Adenomas	Carcinomas	Adenomas	Carcinomas
TGFα/TrsptG37	1B	0.7±0.8	1.1±1.4	40±14b	556±121	36±12	331±55
	1C	0.6±0.9	0.9±1.2	10±6	272±69	8±5	174±40
	1D	0.6±0.8	0.9±1.0	15±9	388±33	12±8	229±20
TrsptG37/+	2B	0.3±0.5	0	10±11	0	10±11	0
	2C	0.3±0.4	0	10±2	0	10±2	0
	2D	0.6±0.9	0.06±0.24	15±4	79	13±3	79
TGFα/+	3A	0.3±0.5	0.5±0.7	5±4	222±35	5±4	187±35
	3B	0.7±0.7	0.7±0.7	23±8	469±106	20±8	388±106
	3C	0.8±0.8	0.6±0.8	18±9	188±20	15±7	145±20
	3D	0.7±1.0	0.8±0.8	21±9	191±50	14±4	155±50
	3E	0.6±0.8	0.7±0.8	30±10	170±38	27±9	142±38
+/+	4A	0	0	0	0	0	0
	4B	0.5±0.8	0.3±0.8	NAc	NAc	NAc	NAc
	4C	0.3±0.7	0	NAc	0	NAc	0
	4D	0.1±0.3	0.1±0.3	NAc	NAc	NAc	NAc
	4E	0	0.3	0	NAc	0	NAc

^aTumor number (see Table 3), size, and area were assessed at necropsy and compared using least square means procedures (see text). Tumor numbers are shown as raw means ± standard deviations. The sizes of approximately 15% of tumors were not measured, including all tumors for Group 4.

^bTumor area and size are shown as geometric means ± standard deviations.

^cNA, no size measure for tumors available.