Table 2. Expression of human RAGE in skin and skin cells*.
Skin in situ | Methods of detection |
---|---|
Young donors: High and middle epidermis Papillary dermis Old donors: Middle and basal epidermis Reticular dermis Enhanced expression in sun-exposed skin |
IHC45,46 |
Skin cell types in vivo Fibroblasts Dendric cells Keratinocytes Endothelial cells Mononuclear cells |
IHC45,46 |
Cell types in vitro | |
---|---|
Resident skin cells Keratinocytes Fibroblasts Melanocytes |
qRT-PCR,46 WB47 WB,43,45 qRT-PCR43,45 ? |
Immune cells and other cell types Mononuclear phagocytes48 Dendritic cells49 T-lymphocytes50 Vascular dermal endothelial cells |
WB,48 IF48 FC49 qRT-PCR50 qRT-PCR,51 WB51 |
FC, flow cytometry; IHC, immunohistochemistry; IF, immunofluorescence; qRT-PCR, quantitative real-time PCR; all other abbreviations are already explained in the text.