Table 4. Multivariable models to demonstrate association of endothelial cell parameters in HIV-infected individuals (n = 217).

Variable	Low endothelial cell density§		High polymegathism§ (cell variation)		Low hexagonality index§ (cell shape not 6-sided)
	OR	P-value	OR	P-value
Gender
Male	1		1		1
Female	0.43 (0.19–0.91)	0.04	2.19 (0.81–5.86)	0.12	0.99 (0.44–2.29)		0.98
Age (years)
30–39	1		1		1
40–49	2.84 (1.35–5.97)		1.00 (0.43–2.31)		0.63 (0.30–1.34)
>50	5.42 (2.21–13.26)	<0.0001*	2.44 (0.97–6.13)	0.09*	1.69 (0.71–3.98)		0.12
Work location
Outdoor worker	0.57 (0.29–1.12)		2.20 (1.00–4.90)		1.97 (1.00–3.95)
Indoor worker	1	0.11	1	0.05	1		0.05
Cigarette smoker
No	1		1		1
Yes	1.04 (0.39–2.78)	0.93	3.41 (1.13–10.31)	0.03	1.09 (0.39–3.06)		0.87
History of eye condition
No	1		1		1
Yes	1.04 (0.44–2.49)	0.93	0.95 (0.37–2.49)	0.93	0.18 (0.05–0.62)		0.01
WHO clinical stage
1/2	1		1		1
3/4	1.58 (0.71–3.51)	0.26	1.88 (0.80–4.54)	0.16	1.11 (0.52–2.33)		0.79
Peak viral load
<10,000 copies	1		1		1
>10,000 copies	0.65 (0.32–1.31)	0.23	0.87 (0.40–1.86)	0.71	0.84 (0.42–1.69)		0.62
Current CD4 count
<200 cells/µl	2.77 (1.12–6.81)		1.30 (0.49–3.48)		0.62 (0.24–1.61)
>200 cells/µl	1	0.03	1	0.60	1		0.33

^§Adjusted for all other variables in model.

^* = test for trend.