Skip to main content
. 2013 Feb 27;8(2):e57777. doi: 10.1371/journal.pone.0057777

Table 2. Transition probabilities (per patient, per 6-month cycle) related to first-line treatment and second-line treatment and probabilities of AIDS event.

Health state CD4 (cell count /mL) HIV RNA (copies/mL) Transition ProbabilitiesLPV/r (first line) Transition Probabilities ATV+r 1 (first line) Transition Probabilities ATV+r 2* (first line) Transition Probabilities (second line) AIDS probabilities
1 > 350 < 50 0.70721 0.77487 0.7232 0.49504 0.0009
2 > 350 ≥ 50 0.86111 0.71106 0.86980 0.60277 0.0162
3 201–350 < 50 0.38737 0.29664 0.40847 0.27118 0.0104
4 201–350 ≥ 50 0.45253 0.36481 0.47386 0.31675 0.0585
5 50–200 < 50 0.05202 0.08941 0.05719 0.0364 0.0212
6 50–200 ≥ 50 0.13132 0.09041 0.14281 0.09191 0.2276
7 < 50 < 50 0.01623 0.00485 0.01791 0.01134 0.6934
8 < 50 ≥ 50 0.02844 0.02175 0.03135 0.01988 0.9435

diagonal elements of transition matrix expressing the probability of remaining in the same health state after one Markov cycle (semester)

*

transitions based on a 19% lesser likelihood of transitioning to a state with greater viral load than when receiving LPV/r