Table 6. Lifetime results of the model divided per treatment.
Parameter | LPV/r | ATV+r 1 | ATV+r 2 |
Survival years (mean) | 24.061 | 24.081 | 24.084 |
QALYs (mean) | 13.322 | 13.060 | 13.261 |
Per capita mean annual cost (€) | 8,477.09 | 8,624.77 | 8,548.21 |
Total cost (€) | 203,967,086 | 207,693,086 | 205,875,090 |
Total cost per QALY (€) | 15,310.56 | 15,902.99 | 15,524.85 |
Years on first-line therapy (mean) | 11.711 | 11.143 | 13.466 |
Patients ending in first-line therapy (%) | 33.43 | 30.92 | 41.12 |
Patients with at least 1 CHD event (%) | 9.94 | 9.81 | 9.77 |
Patients with at least 1 CKD event (%) | 41.34 | 58.93 | 63.65 |
Total CHD events (events per 1000 patient-years) | 6.6 | 6.5 | 6.4 |
Total AIDS events (events per 1000 patient-years) | 49.5 | 54.9 | 46.1 |
Total CKD events (events per 1000 patient-years) | 27.1 | 110.9 | 135.3 |
Total OI events (events per 1000 patient-years) | 35.4 | 35.4 | 35.4 |
Total treatment emergent AE (events per 1000 patient-years) | 17.7 | 14.1 | 16.9 |
Two consecutive cycles with VL ≥ 50 copies/mL (events per 1000 patient-years) | 17.2 | 20.4 | 14.3 |
Total patient-years | 12,030,423 | 12,040,386 | 12,041,769 |
Population size | 500,000 | 500,000 | 500,000 |
QALY: Quality-adjusted life years; CHD: Coronary heart disease; CKD: Chronic kidney disease; OI: Opportunistic infection; AE: Adverse event; VL: Viral load.