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. 2013 Feb 27;8(2):e57777. doi: 10.1371/journal.pone.0057777

Table 6. Lifetime results of the model divided per treatment.

Parameter LPV/r ATV+r 1 ATV+r 2
Survival years (mean) 24.061 24.081 24.084
QALYs (mean) 13.322 13.060 13.261
Per capita mean annual cost (€) 8,477.09 8,624.77 8,548.21
Total cost (€) 203,967,086 207,693,086 205,875,090
Total cost per QALY (€) 15,310.56 15,902.99 15,524.85
Years on first-line therapy (mean) 11.711 11.143 13.466
Patients ending in first-line therapy (%) 33.43 30.92 41.12
Patients with at least 1 CHD event (%) 9.94 9.81 9.77
Patients with at least 1 CKD event (%) 41.34 58.93 63.65
Total CHD events (events per 1000 patient-years) 6.6 6.5 6.4
Total AIDS events (events per 1000 patient-years) 49.5 54.9 46.1
Total CKD events (events per 1000 patient-years) 27.1 110.9 135.3
Total OI events (events per 1000 patient-years) 35.4 35.4 35.4
Total treatment emergent AE (events per 1000 patient-years) 17.7 14.1 16.9
Two consecutive cycles with VL ≥ 50 copies/mL (events per 1000 patient-years) 17.2 20.4 14.3
Total patient-years 12,030,423 12,040,386 12,041,769
Population size 500,000 500,000 500,000

QALY: Quality-adjusted life years; CHD: Coronary heart disease; CKD: Chronic kidney disease; OI: Opportunistic infection; AE: Adverse event; VL: Viral load.