Table 3. Regression slope (95% confidence interval) for three-year changes in percent stenosis per nm increase in on-study LDL-peak diameter and per mmol/L increase LDL-cholesterol subfraction concentrations.

Adjustment	All	Lesions with ≥50% stenosis at baseline	Lesions with 30–49% stenosis at baseline	Lesions with 0–29% stenosis at baseline
LDL-peak
Standard covariates	−0.98	−0.44	−1.22	−1.51
	(−1.84, −0.12)	(−3.1, 2.22)	(−2.85, 0.42)	(−2.77, −0.25)
	P = 0.03	P = 0.75	P = 0.15	P = 0.02
Standard covariates & group	−0.58	−0.18	−1.01	−1.00
	(−1.48, 0.33)	(−3.03, 2.67)	(−2.79, 0.77)	(−2.39, 0.39)
	P = 0.22	P = 0.90	P = 0.27	P = 0.16
Standard covariates, group & lipids	−0.77	−1.37	−1.49	−1.35
	(−1.87, 0.34)	(−4.67, 1.94)	(−3.66, 0.67)	(−3.04, 0.34)
	P = 0.18	P = 0.42	P = 0.18	P = 0.12
LDL-I
Standard covariates	−0.06	3.08	−0.26	−2.02
	(−3.81, 3.69)	(−7.91, 14.06)	(−7.29, 6.77)	(−7.58, 3.54)
	P = 0.97	P = 0.58	P = 0.94	P = 0.48
Standard covariates & group	−1.57	2.12	−1.25	−3.49
	(−5.23, 2.09)	(−9.08, 13.32)	(−8.48, 5.98)	(−9.02, 2.05)
	P = 0.40	P = 0.71	P = 0.73	P = 0.22
Standard covariates, group & lipids	−1.74	−1.51	−1.34	−6.09
	(−6.36, 2.87)	(−15.49, 12.47)	(−10.4, 7.71)	(−13.11, 0.93)
	P = 0.46	P = 0.83	P = 0.77	P = 0.09
LDL-IIa
Standard covariates	−1.37	−2.34	−2.23	−0.52
	(−4.32, 1.57)	(−11.57, 6.88)	(−7.71, 3.26)	(−4.94, 3.90)
	P = 0.36	P = 0.62	P = 0.43	P = 0.82
Standard covariates & group	−2.56	−1.50	−3.02	−1.63
	(−5.44, 0.33)	(−11.06, 8.06)	(−8.71, 2.67)	(−6.11, 2.85)
	P = 0.09	P = 0.76	P = 0.30	P = 0.48
Standard covariates, group & lipids	−2.92	−5.18	−3.78	−2.82
	(−6.38, 0.53)	(−16.69, 6.32)	(−10.62, 3.05)	(−8.16, 2.52)
	P = 0.10	P = 0.38	P = 0.28	P = 0.30
LDL-IIb
Standard covariates	0.61	2.84	−1.31	1.72
	(−1.56, 2.77)	(−3.55, 9.24)	(−5.34, 2.73)	(−1.52, 4.96)
	P = 0.58	P = 0.39	P = 0.53	P = 0.30
Standard covariates & group	−0.98	2.78	−2.66	−0.06
	(−3.17, 1.21)	(−4.14, 9.7)	(−6.98, 1.66)	(−3.48, 3.35)
	P = 0.38	P = 0.43	P = 0.23	P = 0.97
Standard covariates, group & lipids	−0.77	2.26	−3.13	−0.60
	(−3.34, 1.81)	(−5.53, 10.04)	(−8.20, 1.94)	(−4.60, 3.40)
	P = 0.56	P = 0.57	P = 0.23	P = 0.77
LDL-IIIa
Standard covariates	1.77	0.50	1.29	2.89
	(−0.34, 3.88)	(−5.48, 6.47)	(−2.84, 5.42)	(−0.20, 5.99)
	P = 0.10	P = 0.87	P = 0.54	P = 0.07
Standard covariates & group	0.51	0.39	0.45	1.11
	(−1.83, 2.85)	(−7.00, 7.78)	(−4.40, 5.30)	(−2.49, 4.72)
	P = 0.67	P = 0.92	P = 0.86	P = 0.55
Standard covariates, group & lipids	0.85	1.19	0.90	0.73
	(−1.60, 3.30)	(−6.58, 8.96)	(−4.35, 6.15)	(−3.07, 4.52)
	P = 0.50	P = 0.76	P = 0.74	P = 0.71
LDL-IIIb
Standard covariates	9.67	−1.41	9.50	23.29
	(3.80, 15.55)	(−17.88, 15.05)	(−1.91, 20.92)	(15.27, 31.3)
	P = 0.002	P = 0.87	P = 0.11	P = 1.2×10−8
Standard covariates & group	7.20	−2.67	8.27	21.78
	(1.04, 13.35)	(−20.15, 14.81)	(−3.92, 20.47)	(13.05, 30.52)
	P = 0.02	P = 0.77	P = 0.19	P = 10−6
Standard covariates, group & lipids	8.15	−0.10	9.76	22.60
	(1.73, 14.56)	(−18.48, 18.29)	(−3.30, 22.82)	(13.44, 31.75)
	P = 0.01	P = 0.99	P = 0.15	P = 10−6
LDL-IVa
Standard covariates	20.51	3.12	30.09	32.08
	(6.91, 34.12)	(−39.62, 45.87)	(3.68, 56.51)	(11.92, 52.24)
	P = 0.002	P = 0.89	P = 0.03	P = 0.002
Standard covariates & group	14.62	−1.40	26.78	25.58
	(0.92, 28.32)	(−45.27, 42.46)	(−0.61, 54.18)	(4.7, 46.46)
	P = 0.04	P = 0.95	P = 0.06	P = 0.02
Standard covariates, group & lipids	15.89	2.20	30.17	25.08
	(1.68, 30.11)	(−43.06, 47.47)	(1.48, 58.85)	(3.19, 46.98)
	P = 0.03	P = 0.92	P = 0.04	P = 0.03
LDL-IVb
Standard covariates	19.05	13.07	33.73	28.15
	(0.87, 37.22)	(−50.85, 76.99)	(−0.82, 68.28)	(1.08, 55.23)
	P = 0.04	P = 0.69	P = 0.06	P = 0.04
Standard covariates & group	11.24	6.13	28.20	21.07
	(−6.85, 29.32)	(−59.49, 71.75)	(−8.04, 64.43)	(−6.60, 48.74)
	P = 0.23	P = 0.86	P = 0.13	P = 0.14
Standard covariates, group & lipids	12.78	12.98	33.51	19.31
	(−6.18, 31.74)	(−55.65, 81.61)	(−5.07, 72.09)	(−9.94, 48.55)
	P = 0.19	P = 0.71	P = 0.09	P = 0.20