Figure 5. L. monocytogenes strain with a modified InlA causes the release of higher concentration of IL-6 and CCL2.

(A and B) BMMC were incubated with media alone, WT or EGDe L. monocytogenes at the MOI indicated for 2 h, washed and transferred to media containing 50 µg/ml gentamicin for an additional 24 h. Cell supernatants were harvested after the initial 2 h (open bars) and the additional 24 h (grey bars). (A) IL-6 and (B) CCL2 concentrations were determined by ELISA. Data are mean +/- SEM. Statistical significance between WT and EGDe treated at p<0.05 (*) and p<0.01 (**) is indicated.