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. 2013 Feb 27;8(2):e57166. doi: 10.1371/journal.pone.0057166

Table 2. Odds of increased respiratory impairment given various subject characteristics (race, atopic status and inhaled steroid use [n (%)]; age and lung function [mean (SD)]).

IC 0/1n = 24 IC 2/3n = 16 OR* 95% CI
Race, Caucasian 15 (63) 11 (69) 1.32 0.35, 5.05
Atopy, positive 6 (32) 7 (53.8) 2.53 0.59, 10.86
Age (years) 61.8 (11.5) 61.3 (7.7) 1.00 0.94, 1.10
Inhaled steroid use 7 (29.2) 9 (56.3) 3.12 0.83, 11.72
FEV1 percent predicted 91.6 (12. 6) 70.5 (12.0) 0.82** 0.71, 0.94
PC20-FEV1 (methacholine, mg/ml) 9.1 (6.9) 3.4 (5.1) 0.86** 0.76, 0.97
Change of FEV1 (L) −1.2 (0.5) −1.8 (0.5) 0.06** 0.01, 0.49
Change of PC20-FEV1 (mg/ml) 4.0 (8.0) −1.6 (9.1) 0.90 0.81, 1.02
Years from initial diagnosis 25.8 (6.4) 22. 6 (7.2) 0.87 0.76, 1.01
Years from last exposure 17.1 (8.3) 16.8 (10.9) 1.00 0.93, 1.07
Change of FEV1 per year (L) −.06 (.05) −0.08 (0.04) 0.005** 0.00, 0.55

Italics depicts the 3 components of the impairment score.

*

Odds of being in IC 2/3 versus IC 0/1 with given characteristic, from logistic regression model with, in each analysis, adjustment for age (except for fevpp, where age is already incorporated, and for race, atopy, inhaled steroids) and years since last exposure (except for race, atopy, inhaled steroids).

**

p<0.05