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. Author manuscript; available in PMC: 2013 Feb 28.
Published in final edited form as: Neuroscience. 2008 Jun 19;158(3):983–994. doi: 10.1016/j.neuroscience.2008.06.025

Fig. 4.

Fig. 4

Confocal micrographs showing claudin-5 immunoreactivity after 3 h of reperfusion following 90 min of MCAO in the rat. (A) The nonischemic side show that the claudin-5 (Cy-3) in blood vessels is separated from the astrocytes (GFAP-FITC) surrounding them. The merged images show that the claudin-5 and astrocytes are separate. (B) In the ischemic hemisphere, there is fragmentation and degeneration of the claudin-5 immunoreactivity. Co-localization of claudin-5 and GFAP was seen in the ischemic hemisphere. Adapted from Yang et al., 2007.