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. Author manuscript; available in PMC: 2014 Mar 1.
Published in final edited form as: J Gastroenterol Hepatol. 2013 Mar;28(3):576–583. doi: 10.1111/jgh.12084

TABLE 1.

Liver Tumor Occurrence and Injury

PARAMETERS WILD TYPE KNOCKOUT

Male Female Male Female

Number of mice 25 29 22 23
Number of mice with tumor 0 0 1 8
Mouse age (month) 9–17 9–17 9 9–17
ALT±SD (U/L) 20±3.5 19±2.1 76±70.2* 113±105.6*
ALT±SD (U/L) in mice with tumor 234 174±114.1**
*

p<0.05;

**

p<0.01 compared to wild type of same sex.