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. 2013 Jan 4;2(1):161–172. doi: 10.1002/mbo3.54

Figure 7.

Figure 7

A working model of Crc in modulation of type III secretion system (T3SS) in Pseudomonas aeruginosa. Under the control of CrcZ and CbrAB two-component system, Crc positively influences the ExsA-dependent T3SS through modulating the expression of many genes and the production of some catabolites, which collectively contribute to regulation of T3SS. The key T3SS genes and encoding proteins are shown inside of the circle. The proteins and small molecules with documented regulatory role on T3SS are shown at outside the circle. Dashed line arrows indicate translocation, and solid arrows indicate positive regulation and the T bars indicate negative regulation. BHL, N-butanoyl-l-homoserine lactone; PQS, Pseudomonas quinolone signal; IAA, indole-3-acetic acid.