A 58-year-old man with biopsy proven synovial sarcoma of the left thigh. The patient was restaged by PET/MR after neoadjuvant radiotherapy. (A–C) Remaining pathologically increased glucose metabolism (maximum standardized uptake value 7.2) is observed especially in the solid medial tumor part (A, PET; B, PET/MR fusion), which also shows increased contrast enhancement in the fat-suppressed T1-weighted image after the application of Gd (C), consistent with remaining vital tumor tissue after radiotherapy. (D) High-resolution anatomic MR imaging (T2-weighted image) delivers valuable information for planned tumor resection, e.g., the close proximity of the tumor to the femoral vessels and nerve (arrows).