Table 1.

Reprogramming Factors

Reprogramming Factors	Cell Source	Vector	Other Conditions	References
Mouse Oct3/4, Sox2, Klf4, and c-Myc	MEF	Retrovirus		[1, 8-10]
	ME	Retrovirus	DNA methyltransferase and histone deacetylase inhibitors improve reprogramming efficiency	[6]
	Mouse BMMNCs	Retrovirus		[11]
	Mouse B lymphocytes	Retrovirus	Ectopic expression of C/EBPα or knockdown of Pax5	[12]
	Human cord blood or adult CD34+ cells	Retrovirus		[13]
	Mouse SkM	Retrovirus		[14]
	Mouse hepatocytes, and gastric epithelial cells	Retrovirus		[15]
	Mouse fibroblast and hepatocytes	Adenovirus		[16]
Mouse Oct3/4, Sox2, Klf4, and L-Myc	Human dipose-derived Stem cells	Retrovirus	Chemical inhibitors A83-01, CHIR99021, PD0325901, sodium butyrate, and Y-27632	[17]
Mouse Sox2, Klf4, and c-Myc	Pig fibroblast	Retrovirus	Oct4 is dispensable in generation of pig iPS.	[18]
Mouse Oct3/4, Sox2,and Klf4	Mouse tail and skin fibroblast	Retrovirus	Generates iPS without c-Myc transduction	[4]
Mouse Oct4 and Klf4 with small molecules	MEF	Retrovirus	BIX-01294 and BayK8644 facilities reprogramming	[5]
Mouse Oct4 and Klf4	Mouse neural stem cells	Retrovirus	Neural stem cells endogenously express Sox2	[19]
Mouse Oct4	Mouse hair follicle	Retrovirus	Skin dermal papilla cells express Sox2, c-Myc, and Klf4	[20]
Human Oct4, Sox2, Nanog, and LIN28	Human MSCs, fibroblast	Lentivirus	MSC derived from OCT4knock-in ES/H1	[3]
	Human adipose cells	Nonviral	Minicircle	[ 21]
Human Oct3/4, Sox2, Klf4, and c-Myc	Human skin fibroblast	Retrovirus	Slc7a1 modified fibroblasts	[2]
	Human skin fibroblast	Sendai virus		[22]
Human Oct3/4, Sox2, Klf4, and Glis1	Mouse and human fibroblast	Retrovirus		[23]
Human Oct4 and Sox2	Human fibroblast	Retrovirus	Valproic acid improves reprogramming efficiency	[7]
Human Klf4, c-Myc, Oct4, Sox2 mRNA	Human fibroblast	mRNA		[24]

MEF: mouse embryonic fibroblast; SkM: Skeletal myoblast