TABLE 3.

Association of Key CGH Abnormalities with Biological Features

	11q loss	12 gain	13q loss, heterozygous	13q loss, homozygous	17p loss
IGHV Status (N=71)	N=10	N=13	N=25	N=13	N=4
IGHV Mutated n = 36	2 (20%)	5 (38%)	10 (40%)	11 (85%)	1 (25%)
IGHV Unmutated n=35	8 (80%)	8 (62%)	15 (60%)	2 (15%)	3 (75%)
ZAP70 Status (N=68)	N=9	N=11	N=25	N=13	N=4
ZAP70+ n= 30	8 (89%)	6 (55%)	14 (56%) *	1 (8%)	2 (50%)
ZAP70- n=38	1 (11%)	5 (45%)	11 (44%)	12 (92%)	2 (50%)
CD38 Status (N=71)	N=10	N=13	N=24	N=13	N=4
CD38+ n=22	3 (30%)	7 (54%)	7 (29%) *	1 (8%)	2 (50%)
CD38- n=49	7 (70%)	6 (46%)	17 (71%)	12 (92%)	2 (50%)
Family History (N=75)	N=10	N=14	N=26	N=14	N=4
Familial n=38	1 (10%)	8 (57%)	10 (39%)	10 (71%)	2 (50%)
Sporadic n=37	9 (90%)	6 (43%)	16 (61%)	4 (29%)	2 (50%)

^*All the long deletions are in Zap70-, CD38-