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. 2011 Sep 23;13(3):131–136.

Table 2. The CD markers of Mesenchymal stem cells.


Marker Name Chromosome Cellular expression Role Expression increased by References
CD9 Motility related protein 1 (MRP1) 12p13.3 B1, MZ, pre-B cell Cell adhesion, proliferation, motility, osteoclastogenesis, metastasis supresor, signal transduction SDF1 33
CD13 Aminopeptidase N (APN) 15q25-q26 Myeloid cells, Fibroblasts, osteoclasts, endothelial cells, BM stromal cells, Neuronals synaptic mem- branes Presenting antigens, regulatory role in T cells, angiogenesis TGFβ1, c-Maf 34
CD29 Integrin β1 10p11.2 Th17, fibroblasts, monocytes, mast cells, endothelial cells Cell-cell and cell-matrix interaction, adhesion - 34-38
CD44 H-CAM 11p13 - Cell adhesion and migration, secration and activation of MMP-2, T cell acumulation - 17,33, 34
CD49e Integrin α5 (VLA-5) 12q11-q13 T cells, B cells, monocytes Cell migration, development and survival, signal trans- duction (RTK/Ras/Erk) - 34
CD54 ICAM1 19p13.3-p13.2 Leukocytes Innate and adaptive immune, tumor cell growth arrest - 33,34
CD55 Decay-accelerating factor (DAF) 1q32 Many cell types(RBC,WBC) Inhibition of complement activation - 33
CD71 Transferrin receptor 3q29 Erythroid lineage Iron uptake, Erk-MAPK signaling - 33
CD73 5-terminal nucleotidase 6q14-q21 B cells and T cells, lymphatic vessels Prevent TRALI-induced apoptosis, suppression of pro-inflammatory process HIF-1 33, 34
CD90 Thy1 glycoprotein 11q23.3 Neurons, fibroblasts Apoptotic signaling, tumor suppression , Thy1 signaling Iron level 33, 35
CD105 Endoglin 9q33-q34.1 Endothelial cells, monocytes Angiogenesis, TGFβ/ ALK1 signaling, anti-apoptotic effect Hypoxia, TGFβ1 17, 33, 34
CD123 IL3RA Xp22.3 or Yp11.3 Plasmacytoid dendritic cells STAT5 and c-fos activation - 33
CD124 IL4R 16p12.1-p11.2 B and T cells IL4Rα signaling, immune modulation - 33
CD126 IL6R 1q21 Hepatocytes, neutrophils, monocytes/macrophage, lymphocytes Signal transduction, JAK1/ Tyk2 and Ras activation - 33
CD127 IL7R 5p13 NaÏve T cells, granulosa cells, cumulus cells, preovulatory oocytes T cell survival, upregulation of Bcl2 and Glut1 Foxo1 33
CD166 ALCAM (Activated leukocyte cell adhesion molecule) 3q13.1 Neurons, T cells, monocytes - - 17, 33, 34
ASMA α-smooth muscle actin 10q23.3 - - - 34
CD271 Low affinty nerve growth factor receptor (LNGFR) 17q21-q22 - - - 39