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. 2011 Dec 22;13(4):203–212.

Table 3. Effects of mycoplasma contaminations on cell cultures.


Increased sensitivity to apoptosis
Chromosomal aberrations
Change of gene expression patterns
Changes in cell membrane antigenicity
Inhibition of cell growth
DNA fragmentation due to mycoplasma nucleases
Compromised production of viruses
Inhibition of cell metabolism
Reduction of transfection efficiencies
Cell death