Table 3. Effects of mycoplasma contaminations on cell cultures.
Increased sensitivity to apoptosis |
---|
Chromosomal aberrations |
Change of gene expression patterns |
Changes in cell membrane antigenicity |
Inhibition of cell growth |
DNA fragmentation due to mycoplasma nucleases |
Compromised production of viruses |
Inhibition of cell metabolism |
Reduction of transfection efficiencies |
Cell death |