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Effect of KGF on MMP-9 expression in pancreatic cancer cells. (A) qRT-PCR analysis showed significant increases in MMP-9 mRNA levels at 3 h after the addition of 10 ng/ml rhKGF to MIA PaCa-2 cells (p<0.05). (B) Effects of sh-KGF on the expression of MMP-9. qRT-PCR revealed that KGF shRNA significantly reduced KGF and MMP-9 mRNA levels in KLM-1 cells compared with the control shRNA (p<0.001 and p<0.05, respectively).
