Table I.

Correlation of clinicopathological features and KGF, KGFR, MMP-9 or co-expression of KGF and KGFR in pancreatic cancers.

		KGF		KGFR		MMP-9		KGF and KGFR
Variables	No.	No. (%)	P-value	No. (%)	P-value	No. (%)	P-value	No. (%)	P-value
Gender
Male	40	16 (40)	NS	18 (45)	NS	21 (53)	NS	10 (25)	NS
Female	23	11 (48)		5 (22)		14 (61)		4 (17)
Age
<65	30	13 (43)	NS	9 (30)	NS	16 (53)	NS	4 (13)	NS
≥65	33	14 (42)		14 (42)		19 (58)		10 (30)
UICC classification
T-primary tumor
T1	4	2 (50)	NS	2 (50)	NS	2 (50)	NS	1 (25)	NS
T2	4	1 (25)		1 (25)		2 (50)		1 (25)
T3	18	11 (61)		7 (39)		11 (61)		5 (28)
T4	37	13 (35)		13 (35)		20 (54)		7 (19)
N-regional lymph nodes
N0	23	12 (52)	NS	11 (48)	NS	15 (65)	NS	6 (26)	NS
N1	40	15 (38)		12 (30)		20 (50)		8 (20)
M-distant metastasis
M0	61	26 (43)	NS	22 (36)	NS	34 (56)	NS	13 (21)	NS
M1	2	1 (50)		1 (50)		1 (50)		1 (50)
G-histological grading
G1	34	11 (32)	NS	14 (41)	NS	20 (59)	NS	6 (18)	NS
G2	26	13 (50)		8 (31)		12 (46)		7 (27)
G3	3	3 (100)		1 (33)		3 (100)		1 (33)
G4	0	0		0		0		0
Stage
I or II	11	6 (55)	NS	5 (45)	NS	5 (45)	NS	4 (36)	NS
III or IV	52	21 (40)		18 (35)		30 (58)		10 (19)
Other tumor characteristics
Lymphatic invasion
Negative	8	4 (50)	NS	3 (38)	NS	5 (63)	NS	2 (25)	NS
Positive	55	23 (42)		20 (36)		30 (55)		12 (22)
Venous invasion
Negative	40	12 (30)	0.0065	11 (28)	0.05	19 (48)	0.0082	5 (13)	0.014
Positive	23	15 (65)		12 (52)		16 (70)		9 (39)
Nerve invasion (intrapancreatic)
Negative	14	8 (57)	NS	6 (43)	NS	9 (64)	NS	3 (21)	NS
Positive	49	19 (39)		17 (35)		26 (53)		11 (22)