Table II.
A, Hypermethylation alterations | ||
---|---|---|
| ||
In UCM | ||
|
||
Hyper-methylateda | Non-hyper-methylated | |
In CW-2 | ||
Hypermethylated | 62 | 421 |
Non-hypermethylated | 86 | 12946 |
Odds ratio = 22.15 | ||
95% CI 15.48–31.56 | ||
Fisher’s exact test P<2.2×10−16 | ||
| ||
B, Hypomethylation alterations | ||
| ||
In UCM | ||
|
||
Hyper-methylatedb | No hyper-methylated | |
| ||
In CW-2 | ||
Hypomethylated | 27 | 102 |
Non-hypomethylated | 91 | 13295 |
Odds ratio = 38.63 | ||
95% CI 23.13–62.91 | ||
Fisher’s exact test P<2.2×10−16 |
Spots hypermethylated in 3 or more UCM samples.
Spots hypo-methylated in 3 or more UCM samples. The total number of spots is 13,515 after filtering the 30% lowest-intensity spots from the 19,308 methylation-sensitive spots printed on the MS-AFLP array. The number of spots without changes is an over-estimation because they include other loci that were not sufficiently amplified in the respective experiments.