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. Author manuscript; available in PMC: 2013 Feb 28.
Published in final edited form as: J Infect Dis. 2008 Dec 15;198(12):1862–1869. doi: 10.1086/593213

Table 1.

Bacterial clearance after nontypeable Haemophilus influenzae (NTHi) inoculation of the middle ear (ME) cavity.

Time after NTHi inoculation C57BL/6 mice
MyD88−/− mice
CPPs, proportion Bacterial colonization of CPPs,a mean CPPs, proportion Bacterial colonization of CPPs,a mean
Day 1 4/6 4 6/6 4
Day 2 6/6 3 6/6 4
Day 3 3/6 1 6/6 4
Day 5 0/6 0 6/6 4
Day 10 0/6 0 6/6 4
Day 14 0/6 0 6/6 2.7

NOTE. No colony-forming units were detected by day 5 after NTHi inoculation in C57BL/6 (wild-type [WT]) mice. Bacterial clearance was impaired in myeloid differentiation primary response gene 88 (MyD88)−/− mice; NTHi were isolated from more than half of the MEs of MyD88−/− mice through 21 days after inoculation. CPPs, culture-positive plates.

a

For the semiquantitative analysis of bacterial colonization of the MEs of WT vs. MyD88−/− mice after NTHi inoculation, 0 indicates no colony-forming units, 1 indicates colony-forming units in 1 quadrant, 2 indicates colony-forming units in 2 quadrants, 3 indicates colony-forming units in 3 quadrants, and 4 indicates colony-forming units in all 4 quadrants.