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. Author manuscript; available in PMC: 2013 Feb 28.
Published in final edited form as: N Engl J Med. 2003 Jul 17;349(3):247–257. doi: 10.1056/NEJMoa022289

Figure 2. Kaplan–Meier Estimates of Overall Survival among Patients with Stage II or Stage III Colon Cancer According to Treatment Status.

Figure 2

Patients with tumors exhibiting microsatellite stability or low-frequency microsatellite instability who received adjuvant chemotherapy had a significant increase in overall survival as compared with patients who received no adjuvant chemotherapy (hazard ratio for death, 0.69 [95 percent confidence interval, 0.50 to 0.94]; P=0.02) (Panel A). Among patients with tumors exhibiting high-frequency microsatellite instability, there was no significant difference in the duration of overall survival between patients who received adjuvant chemotherapy and those who did not (hazard ratio for death, 2.17 [95 percent confidence interval, 0.84 to 5.55]; P=0.10) (Panel B). The analysis included data for eight years from the date of randomization.