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. 2013 Jan 18;45(1):e5. doi: 10.1038/emm.2013.10

Figure 5.

Figure 5

In vivo production of interleukin (IL)-6 induced by IL-17A, but not by lipopolysaccharide (LPS), is inhibited by acetylsalicylic acid (ASA) treatment. (ac) LPS was administered into wild-type mouse airways for 3 days with and without intraperitoneal treatment with ASA. (a) Bronchoalveolar lavage (BAL) cellularity. (b) BAL IL-6 levels. (c) Flow cytometric analysis of lung dendritic cell (DC) maturation. Lung DCs were stained with anti-CD11c, anti-CD11b, anti-CD80 and anti-CD86 Abs. (d, e) LPS and rIL-17 were administered into WT mouse airways for 3 days with and without intraperitoneal treatment with ASA. (d) BAL cellularity. (e) IL-6 levels in BAL fluid. PBS, phosphate-buffered saline. *P<0.05.