Table 3.

Results of Random Effects Logistic Regression Analyses for Odds of Major Depressive Episode (MDE) from Baseline Through Visit 9 by Menopausal Status

	Model A OR (95% CI)	Model B OR (95% CI)	Model C OR (95% CI)
Variables
Age	0.99 (0.90, 1.09)	0.96 (0.86, 1.06)	0.95 (0.86, 1.05)
Menopausal status (ref=pre)
Perimenopause	2.20 (1.17, 4.16)	2.08 (1.06, 4.08)	1.98 (1.00, 3.92)
Postmenopause	3.57 (1.35, 9.39)	4.32 (1.54, 12.13)	3.86 (1.36, 10.92)
African American	1.96 (0.96, 3.97)	1.64 (0.82, 3.29)	1.56 (0.78, 3.15)
History of major depression at baseline		3.02 (1.57, 5.80)	2.98 (1.55, 5.72)
Psychotropic medication use		4.71 (2.65, 8.38)	4.55 (2.55, 8.09)
Very upsetting life event		2.66 (1.59, 4.47)	2.62 (1.56, 4.40)
BMI continuous		1.04 (.099, 1.09)	1.04 (1.00, 1.09)
Frequent VMS (≥6 days/past 2 weeks)			1.76 (0.99, 3.11).

Model A: adjusted for age and race

Model B: addition of history of major depression at baseline, annual psychotropic medication, annual very upsetting life events, BMI

Model C: final model with addition of annual frequent VMS