Table 1.
Baseline patient characteristics according to total patients, CRP and NLR level
Characteristics |
Total patients (n = 318) |
Patients grouped by CRP level (n = 318) |
Patients grouped by NLR level (n = 318) |
||
---|---|---|---|---|---|
CRP ≤ 6.3 mg/L (n = 171) | CRP > 6.3 mg/L (n = 147) | NLR ≤ 2.3 (n = 129) | NLR > 2.3 (n = 189) | ||
Sex (male:female) |
240:78 |
122:49 |
118:29 |
93:36 |
147:42 |
Age (years) |
58 (32–89) |
59 (33–80) |
58 (32–89) |
58 (33–80) |
59 (32–89) |
Cause (HBV/HCV/Alcohol/Others, %) |
242 (76.1)/ 33 (10.4)/ 25 (7.9) / 18 (5.7) |
123 (71.9)/ 26 (15.2)/ 12 (7.0)/ 10 (5.8) |
119 (81.0)/ 7 (4.8)/ 13 (8.8)/ 8 (5.4) |
100 (77.5)/ 14 (10.9)/ 8 (6.2)/ 7 (5.4) |
142 (75.1)/ 19 (10.1)/ 17 (9.0)/ 11 (5.8) |
Platelet counts (×103/mm3) |
139.6 ± 86.5 |
121.1 ± 63.9 |
161.1 ± 103.1 |
121.8 ± 64.9 |
151.7 ± 96.9 |
ALT (IU/L) |
39.0 (1.0–2,430.0) |
35.0 (1.0–2,430.0) |
42.0 (6.0–503.0) |
39.0 (1.0–2,430.0) |
39.0 (6.0–503.0) |
Total bilirubin (mg/dL) |
1.0 (0.2–26.9) |
0.9 (0.2–9.4) |
1.2 (0.2–26.9) |
0.9 (0.2–7.8) |
1.1 (0.2–26.9) |
Albumin (g/dL) |
3.5 ± 0.6 |
3.7 ± 0.4 |
3.4 ± 0.5 |
3.6 ± 0.6 |
3.5 ± 0.6 |
Prothrombin time (%) |
79.4 ± 18.0 |
81.3 ± 17.6 |
77.1 ± 18.2 |
80.4 ± 18.4 |
78.6 ± 17.7 |
Child-Pugh class (A/ B/ C, %) |
200 (62.9)/ 91 (28.6)/ 27 (8.5) |
128 (74.9)/ 36 (21.1)/ 7 (4.1) |
72 (49.0)/ 55 (37.4)/ 20 (13.6) |
99 (76.7)/ 26 (20.2)/ 4 (3.1) |
101 (53.4)/ 65 (34.4)/ 23 (12.2) |
Tumor size (cm) |
5.5(0.8–26.5) |
3.0 (0.8–18.6) |
10.0 (1.0–26.5) |
3.0 (0.8–17.4) |
7.9 (1.3–26.5) |
Tumor number, solitary (%) |
144 (45.3) |
93 (54.4) |
51 (34.7) |
74 (57.4) |
70 (37.0) |
Presence of PVT (%) |
107 (33.6) |
24 (14.0) |
83 (56.5) |
23 (17.8) |
84 (44.4) |
Presence of metastasis (%) |
62 (19.5) |
14 (8.2) |
48 (32.7) |
11 (8.5) |
51 (27.0) |
Tumor stage (I/ II/ III/ IVa/ IVb, %) |
41 (12.9)/ 76 (23.8)/ 85 (26.7)/ 64 (20.1)/ 52 (16.4) |
34 (19.9)/ 57 (33.3)/ 51 (29.8)/ 17 (9.9)/ 12 (7.0) |
7 (4.8)/ 19 (12.9)/ 34 (23.1)/ 47 (32.0)/ 40 (27.2) |
30 (23.3)/ 40 (31.0)/ 35 (27.1)/ 18 (14.0)/ 6 (4.7) |
11 (5.8)/ 36 (19.0)/ 50 (26.5)/ 46 (24.3)/ 46 (24.3) |
AFP (ng/mL) |
92.3 (1.6–2,753,500.0) |
28.9 (1.6–331,580.0) |
350.0 (2.2–2,753,500.0) |
32.3 (1.7–331,580.0) |
207.1 (1.6–2,753,500.0) |
CRP (mg/L) |
4.7 (0.1–343.6) |
1.2 (0.1–6.3) |
24.9 (6.4–343.6) |
1.7 (0.1–64.8) |
14.3 (0.2–343.6) |
NLR | 2.6 (0.6–49.9) | 1.8 (0.6–13.0) | 4.0 (0.7–49.9) | 1.5 (0.6–2.2) | 3.8 (2.3–49.9) |
CRP, C-reactive protein; NLR, neutrophil-to-lymphocyte ratio; HBV, hepatitis B virus; HCV, hepatitis C virus; ALT, alanine aminotransferase; PVT, portal vein thrombosis; AFP, α-fetoprotein.