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. 2013 Feb 15;13:78. doi: 10.1186/1471-2407-13-78

Table 1.

Baseline patient characteristics according to total patients, CRP and NLR level

Characteristics
Total patients (n = 318)
Patients grouped by CRP level (n = 318)
Patients grouped by NLR level (n = 318)
    CRP ≤ 6.3 mg/L (n = 171) CRP > 6.3 mg/L (n = 147) NLR ≤ 2.3 (n = 129) NLR > 2.3 (n = 189)
Sex (male:female)
240:78
122:49
118:29
93:36
147:42
Age (years)
58 (32–89)
59 (33–80)
58 (32–89)
58 (33–80)
59 (32–89)
Cause (HBV/HCV/Alcohol/Others, %)
242 (76.1)/ 33 (10.4)/ 25 (7.9) / 18 (5.7)
123 (71.9)/ 26 (15.2)/ 12 (7.0)/ 10 (5.8)
119 (81.0)/ 7 (4.8)/ 13 (8.8)/ 8 (5.4)
100 (77.5)/ 14 (10.9)/ 8 (6.2)/ 7 (5.4)
142 (75.1)/ 19 (10.1)/ 17 (9.0)/ 11 (5.8)
Platelet counts (×103/mm3)
139.6 ± 86.5
121.1 ± 63.9
161.1 ± 103.1
121.8 ± 64.9
151.7 ± 96.9
ALT (IU/L)
39.0 (1.0–2,430.0)
35.0 (1.0–2,430.0)
42.0 (6.0–503.0)
39.0 (1.0–2,430.0)
39.0 (6.0–503.0)
Total bilirubin (mg/dL)
1.0 (0.2–26.9)
0.9 (0.2–9.4)
1.2 (0.2–26.9)
0.9 (0.2–7.8)
1.1 (0.2–26.9)
Albumin (g/dL)
3.5 ± 0.6
3.7 ± 0.4
3.4 ± 0.5
3.6 ± 0.6
3.5 ± 0.6
Prothrombin time (%)
79.4 ± 18.0
81.3 ± 17.6
77.1 ± 18.2
80.4 ± 18.4
78.6 ± 17.7
Child-Pugh class (A/ B/ C, %)
200 (62.9)/ 91 (28.6)/ 27 (8.5)
128 (74.9)/ 36 (21.1)/ 7 (4.1)
72 (49.0)/ 55 (37.4)/ 20 (13.6)
99 (76.7)/ 26 (20.2)/ 4 (3.1)
101 (53.4)/ 65 (34.4)/ 23 (12.2)
Tumor size (cm)
5.5(0.8–26.5)
3.0 (0.8–18.6)
10.0 (1.0–26.5)
3.0 (0.8–17.4)
7.9 (1.3–26.5)
Tumor number, solitary (%)
144 (45.3)
93 (54.4)
51 (34.7)
74 (57.4)
70 (37.0)
Presence of PVT (%)
107 (33.6)
24 (14.0)
83 (56.5)
23 (17.8)
84 (44.4)
Presence of metastasis (%)
62 (19.5)
14 (8.2)
48 (32.7)
11 (8.5)
51 (27.0)
Tumor stage (I/ II/ III/ IVa/ IVb, %)
41 (12.9)/ 76 (23.8)/ 85 (26.7)/ 64 (20.1)/ 52 (16.4)
34 (19.9)/ 57 (33.3)/ 51 (29.8)/ 17 (9.9)/ 12 (7.0)
7 (4.8)/ 19 (12.9)/ 34 (23.1)/ 47 (32.0)/ 40 (27.2)
30 (23.3)/ 40 (31.0)/ 35 (27.1)/ 18 (14.0)/ 6 (4.7)
11 (5.8)/ 36 (19.0)/ 50 (26.5)/ 46 (24.3)/ 46 (24.3)
AFP (ng/mL)
92.3 (1.6–2,753,500.0)
28.9 (1.6–331,580.0)
350.0 (2.2–2,753,500.0)
32.3 (1.7–331,580.0)
207.1 (1.6–2,753,500.0)
CRP (mg/L)
4.7 (0.1–343.6)
1.2 (0.1–6.3)
24.9 (6.4–343.6)
1.7 (0.1–64.8)
14.3 (0.2–343.6)
NLR 2.6 (0.6–49.9) 1.8 (0.6–13.0) 4.0 (0.7–49.9) 1.5 (0.6–2.2) 3.8 (2.3–49.9)

CRP, C-reactive protein; NLR, neutrophil-to-lymphocyte ratio; HBV, hepatitis B virus; HCV, hepatitis C virus; ALT, alanine aminotransferase; PVT, portal vein thrombosis; AFP, α-fetoprotein.

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