Fig 3.
Histopathology of B. cereus G9241 wild-type and ΔpagA1 or ΔpagA2 mutant disease in mice. C57BL/6 mice were infected with 1 × 105 spores of B. cereus G9241 (A and D) or its ΔpagA1 (B and E) or ΔpagA2 mutant (C and F). Sections from infected spleen and lung tissues were fixed, thin sectioned, and stained with hematoxylin-eosin. Tissue sections were viewed by light microscopy, and images of the spleen (A, B, and C) and lung (D, E, and F) were captured. Low-magnification views are presented on the left, and higher magnifications of the same image are shown on the right of each panel.