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The sse gene, but not spyCEP or scpA, is required for skin invasion by MGAS5005. Shown are representative images of inside-out infection sites at 24 h after subcutaneous infection with 8.4 × 107 CFU MGAS5005 (A), 1.5 × 108 CFU MGAS5005Δsse (B), 8.4 × 107 CFU MGAS5005ΔspyCEP (C), or 1.1 × 108 CFU MGAS5005ΔscpA (D).
