Fig 2.
Analysis of microbiota from miR-155-deficient and control wild-type C57BL/6 mice orally infected with approximately 1 × 109 CFU of C. rodentium. (a) Proportional abundance of C. rodentium in wild-type and miR-155-deficient mice as a percentage of the total microbiota. *** indicates P value of <0.001 as calculated by the Metastats program within the mothur software package. (b) Dendrogram illustrating similarity in overall microbiota community structure between wild-type and miR-155-deficient mice prior to and following C. rodentium infection. W1 to W5, wild-type mice; B1 to B5, miR-155-deficient mice; d0, immediately prior to infection; d4 and d14, day 4 and day 14 postinfection, respectively. Adjacent bars show microbiota composition of each sample. Brown/orange/yellow sections are members of the Bacteroidetes phylum; blue/purple/gray sections are members of the Firmicutes phylum.