Fig 5.

Region of the L. pneumophila chromosome that encodes lpg0273 and proposed structure of Lpg0273. (A) Chromosomal locus of lpg0273. Arrows indicate orientation of the genes. Sizes (bp) of the genes are indicated above, and the predicted function of each gene is listed below. Red indicates genes with significantly elevated expression levels when treated with 5 mM nicotinic acid. Gray indicates genes that are not affected by a 3-h nicotinic acid treatment. (B) Structure of Lpg0273 and ligand binding site (blue) predicted using 3DLigandSite prediction software (71), showing helices typical of MFS transporter proteins.