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sagB is highly similar to sagA and is also required during the early stages of intracellular replication. (A) Comparison of SagB and SagA. The conserved catalytic residues are marked with a box. (B) Intracellular replication in HeLa cells of the 2308 wild-type, ΔsagB, and ΔsagA ΔsagB double mutant strains.
