Table 3.
Comparison of some characteristics of confirmed and culture negative PTB cases admitted with severe pneumonia (N=51)
|
Variable |
Confirmed PTB |
Culture negative PTB |
OR (95% CI) |
p –value |
|---|---|---|---|---|
| n=17 (%) | n=34 (%) | |||
|
History of cough |
|
|
|
|
| >2 weeks (63%) |
12 (71) |
20 (59) |
1.6 (0.4 - 5.8) |
0.41 |
| <2 weeks (37%) |
5 (29) |
14 (41) |
||
|
History of weight loss |
|
|
|
|
| Present (59%) |
11 (65) |
19 (56) |
1.4 (0.4 - 4.8) |
0.5 |
| Absent (41%) |
6 (35) |
15 (44) |
||
|
History of wheezing |
|
|
|
|
| Yes (12%) |
3 (18) |
3 (9) |
2.2 (0.3 - 12.3) |
0.3 |
| No (88%) |
14 (82) |
31 (91) |
||
|
Peripheral lymphadenopathy |
|
|
|
|
| Present (31%) |
5 (29) |
11 (32) |
0.8 (0.2 - 3.0) |
0.8 |
| Absent (69%) |
12 (71 ) |
23 (68) |
||
|
Malnutrition (WHZ) |
|
|
|
|
| Moderate/severe (35%) |
7 (41) |
11 (32) |
1.4 (0.4 - 4.8) |
0.5 |
| None/mild (65%) |
10(59) |
23 (68) |
||
|
Anaemia* |
|
|
|
|
| Mod/severe (82%) |
14 (82) |
28 (82) |
1 (0.2 - 4.6) |
>0.999 |
| None/mild (18%) |
3 (18) |
6 (18) |
||
|
HIV serology |
|
|
|
|
| Positive (28%) |
3 (18) |
11 (32) |
0.4 (0.1 - 1.8) |
0.2 |
| Negative (72%) |
14 (82) |
23 (68) |
||
|
TB contact |
|
|
|
|
| Yes (37%) |
6 (35) |
13 (38) |
0.8 (0.2 - 2.9) |
0.8 |
| No (63%) |
11 (65) |
21 (62) |
||
|
Reduced activity |
|
|
|
|
| Yes (67%) |
13(76.5) |
21(62) |
2.0 (0.5 – 7.5) |
0.2 |
| No (33%) |
4(23.5) |
13(38) |
||
|
CXR |
|
|
|
|
| Abnormal (41%) |
7 (41) |
14 (41) |
1 (0.3 – 3.2) |
>0.999 |
| Normal (59%) |
10 (59) |
20 (14) |
|
|
|
BCG immunisation |
|
|
|
|
| Yes (84%) |
14 (82) |
29 (85) |
0.8 (0.1 - 3.8) |
0.7 |
| No (16%) |
3 (18) |
5 (15) |
||
|
Age group |
|
|
|
|
| Under 1 year (25.5%) |
6 (35) |
7 (21) |
|
0.4 |
| 1 – 5 years (47%) |
6 (35) |
18 (53) |
|
|
| Above 5 years (27.5%) | 5 (29) | 9 (26) |