Table 3.
Changes in selected parameters in Control and RESMENA groups after 8 weeks of nutritional intervention
| Variable |
Control group (n = 48) |
Resmena group (n = 48) |
|
||||
|---|---|---|---|---|---|---|---|
| Visit 1 (day 0) | Visit 2 (day 60) | pa | Visit 1 (day 0) | Visit 2 (day 60) | pb | pc | |
| Weight (kg) |
99.45 ± 19.21 |
92.72 ± 18.50 |
<0.001 |
100.00 ± 16.58 |
92.91 ± 15.76 |
<0.001 |
0.555 |
| BMI (kg/m2) |
36.15 ± 4.95 |
33.70 ± 4.80 |
<0.001 |
35.55 ± 4.40 |
33.03 ± 4.24 |
<0.001 |
0.732 |
| Waist circumference (cm) |
110.94 ± 13.41 |
104.18 ± 12.29 |
<0.001 |
111.25 ± 12.30 |
103.78 ± 11.66 |
<0.001 |
0.432 |
| Waist/hip ratio |
0.96 ± 0.10 |
0.94 ± 0.09 |
<0.001 |
0.96 ± 0.10 |
0.93 ± 0.10 |
<0.001 |
0.355 |
| Bioimpedance Fat mass (kg) |
38.97 ± 10.87 |
33.68 ± 10.22 |
<0.001 |
39.23 ± 9.50 |
33.84 ± 9.09 |
<0.001 |
0.886 |
| DXA Fat mass (kg) |
42.13 ± 10.18 |
37.50 ± 10.39 |
<0.001 |
42.56 ± 9.18 |
37.30 ± 8.95 |
<0.001 |
0.208 |
| TC (mg/dl) |
221 ± 39 |
204 ± 39 |
0.001 |
219 ± 48 |
203 ± 46 |
0.020 |
0.943 |
| HDL-c (mg/dl) |
46 ± 10 |
42 ± 9 |
0.001 |
43 ± 10 |
41 ± 10 |
0.050 |
0.158 |
| LDL-c (mg/dl) |
140 ± 36 |
133 ± 35 |
0.085 |
137 ± 41 |
131 ± 40 |
0.374 |
0.888 |
| TC/HDL-c ratio |
4.94 ± 1.02 |
4.96 ± 0.94 |
0.856 |
5.18 ± 1.24 |
5.04 ± 1.24 |
0.398 |
0.419 |
| LDL-c/HDL-c ratio |
3.09 ± 0.77 |
3.22 ± 0.78 |
0.178 |
3.20 ± 0.83 |
3.23 ± 0.92 |
0.803 |
0.623 |
| TG (mg/dl) |
176 ± 10 |
145 ± 70 |
0.005 |
194 ± 123 |
151 ± 99 |
<0.001 |
0.421 |
| Glucose (mg/dl) |
121.02 ± 33.87 |
107.98 ± 13.71 |
0.006 |
123.81 ± 37.82 |
110.22 ± 26.18 |
0.016 |
0.939 |
| Insulin (IU/mg) |
15.30 ± 11.46 |
9.32 ± 7.18 |
<0.001 |
14.36 ± 8.30 |
9.14 ± 6.13 |
<0.001 |
0.557 |
| HOMA index |
4.69 ± 3.77 |
2.61 ± 2.31 |
<0.001 |
4.48 ± 3.01 |
2.60 ± 2.00 |
<0.001 |
0.686 |
| ALT (U/L) |
37.60 ± 21.04 |
27.03 ± 10.70 |
<0.001 |
29.13 ± 11.59 |
29.28 ± 14.20 |
0.936 |
0.001 |
| AST (U/L) | 25.81 ± 10.84 | 20.68 ± 6.18 | 0.001 | 21.90 ± 6.01 | 22.20 ± 6.14 | 0.740 | 0.002 |
BMI, Body Mass Index; DXA, Dual-energy X-ray Absorptiometry; HDL-c, High Density Lipoprotein-cholesterol; LDL-c, Low Density Lipoprotein-cholesterol; TG, Triglycerides; HOMA, Homeostasis Model Assessment; ALT, Alanine aminotransferase; AST, Aspartate aminotranferase. p < 0.05 was set-up as statistically significant.
pa differences between baseline and final values in Control group. pb differences between baseline and final values in RESMENA group. pc differences between changes in Control group as compared with RESMENA group at the end of the intervention.