Table 3.
Dual Energy X-ray Absorptiometry measurements in children with and without visually obvious lipoatrophy
| Children with lipoatrophy, N=15 | Children without lipoatrophy, N=27 | HIV-uninfected local population norms, N=34 | p-value, adjusted for age and sex (two-tailed)* | |
|---|---|---|---|---|
| Limb fat versus limb lean ratio: mean with 95% confidence interval (95% CI) |
0.36 (0.25 – 0.46) |
0.62 (0.54 – 0.70) |
0.63 (0.56 – 0.70) |
<0.001 |
| Limb fat versus total body weight ratio: mean (95% CI) |
9.9 (8.5 – 11.4) |
13.7 (12.7 – 14.8) |
14.7 (13.7 – 15.7) |
<0.001 |
| Limb fat versus body mass index ratio: mean (95% CI) |
0.12 (0.10 – 0.13) |
0.15 (0.14 – 0.17) |
0.17 (0.16 – 0.19) |
0.001 |
| Total limb fat, kg, mean (95% CI) | 1.7 (1.4 – 2.1) | 2.3 (2.1 – 2.6) | 2.7 (2.4 – 2.9) | 0.01 |
* p-value compares HIV-infected children with and without lipoatrophy.