Figure 2.
Neutropenic and diabetic bacteraemia models differentiate the virulence of A. baumannii clinical isolates. PFGE demonstrating the differences in genotypes among the six A. baumannii clinical isolates used in this study (a). Survival of neutropenic mice (b) or diabetic mice (c) infected via tail vein injection with different clinical isolates of A. baumannii at a 5 × 107 inoculum. n = 8 for all strains except for ATCC 17978, HUMC1 and HUMC4 in the neutropenic mice in which n = 7 and HUMC12 in diabetic mice in which n = 6. *P < 0.005 versus all other treatments, **P < 0.05 versus HUMC1 and HUMC12, and ‡P < 0.007 versus HUMC1 and HUMC6 by log-rank test.