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Effect of CaM or GSH-CaM on Ca2+ transient and cell shortening in normal and failing cardiomyocytes. (A) Representative tracings of Ca2+ transient and cell shortening in normal and failing cardiomyocytes. (B) The characteristics of cell shortening and Ca2+ transient in normal and failing cardiomyocytes treated with RyR2 domain peptides (DPc10, 30 µmol/L, or DP4090–4123, 30 µmol/L).
