Table 2. Evolution of Onchocerca volvulus microfilarial density after ivermectin treatment in ivermectin-naïve and multiply treated subjects.
From D0 to D15 | From D15 to D80 | From D80 to D180 | ||||
Percentage of subjects whose microfilarial density: | Ivermectin-naïve | Multiply treated | Ivermectin- naïve | Multiply treated | Ivermectin- naïve | Multiply treated |
- increased | 0 | 0 | 26.7 | 38.7 | 66.9 | 74.8 |
- decreased | 100 | 100 | 22.1 | 11.3 | 0.9 | 2.1 |
- levelled off* | - | - | 51.2 | 50.0 | 32.2 | 23.1 |
all individuals in this category presented with no detectable skin microfilariae.