TABLE 2.

Experimentally reported ligand entry rates of oxygen migration into Sperm whale myoglobin at pH 7.0

The bimolecular rate constant for ligand entry, k′_entry, was calculated as k′_O2/F_geminate (8). The errors for wild-type (WT) myoglobin were estimated from averages of multiple geminate analyses (>10) (8).

Protein	k′O2 (μm−1 s−1)	k′entry (μm−1 s−1)
wt	16 ± 3	34 ± 7
Ala-E7	53	410
Trp-E7	6,2	8.6