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. 2013 Feb 28;7(2):e2076. doi: 10.1371/journal.pntd.0002076

Table 1. The nonamer CD8+ T cell epitopes on the nucleoprotein of Hantaan virus and their HLA molecule restrictions.

Patients Severity 15-mer peptide Nonamer Nonamer sequence HLA Restriction Frequency of pre-sensitized CD8+ T cells (SFC/106 cells)
Donor1 severe aa127–aa141 aa129–aa137 FVVPILLKA HLA-A2 145–205
Donor2 critical aa127–aa141 aa131–aa139 VPILLKALY HLA-B35 140–190
Donor3 critical aa241–aa255 aa247–aa255 LPDTAAVSL HLA-B35 270–305
Donor4 mild aa163–aa177 aa167–aa175 DVNGIRKPK HLA-A33 360–380
aa277–aa291 aa277–aa285 ETKESKAIR HLA-A33 165–180

HLA, human leukocyte antigen; SFC, spot forming cell.