Figure 3. Summary of indole-diterpene biosynthesis pathway.

Arrows indicate one or more steps catalyzed by products of the genes indicated, where each idt/ltm gene is designated by its final letter (G = idtG/ltmG, etc.). Arrows and genes in blue indicate steps in synthesis of the first fully cyclized intermediate (paspaline). Arrows and genes in red indicate steps in decoration of paspaline to give the variety of indole-diterpenes in the Clavicipitaceae. Structures shown in gray are not yet verified.