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A) von Frey test B) Plantar test The von Frey mechanical withdrawal threshold and plantar thermal withdrawal threshold after crush operation. Control and etanercept groups exhibited mechanical hyperalgesia and thermal hyperalgesia on day 21, with effects attenuated by etanercept therapy (**p<0.01; *p<0.05; ‡p<0.01; †p<0.05, compared to sham group).
