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A, direct binding of affinity purified antibodies to T1DM ((black rhombus), COXSA (black square), CA (black circle) or irrelevant (black triangle) peptides to CA synthetic peptide. Data represent absorbance at 405 nm (vertical axis); antibody concentration µg/ml (horizontal axis). B, Graphical representation of type I diabetes patients’ or controls’ sera binding to CA synthetic peptide.
