Table 2. Association between CES1 mRNA expression level in adipose tissue and measures of glucose and lipid metabolism.
| Response variable | Regression coefficient | P-value |
| HOMA-IR | +15% | 0.003 |
| ISIcomposite | −10% | 0.005 |
| 120-min glucose, OGTT | +3% | 0.23 |
| Fasting triglyceride level | +10% | 0.003 |
| Fasting insulin level | +12% | 0.006 |
| Fasting glucose level | +3% | 0.002 |
| Total cholesterol level | +3% | 0.04 |
The statistical model is: ln(response variable) = age+sex+BMI+CES1 mRNA level. The regression coefficient expresses the change in the response variable associated with a doubling of CES1 mRNA level from its average. CES1: carboxylesterase 1 gene; HOMA-IR: homeostasis model assessment-insulin resistance; ISIcomposite: insulin sensitivity index (composite); OGTT: oral glucose tolerance test.