Figure 2. TB associated cytokines after 4 and 6 weeks of infection.

IL-17 (A) and IL-6 (B) are significantly increased in the infected mice (open symbols) compared with uninfected mice (black symbols) at 4 weeks after infection. At 6 weeks post infection levels in all infected and non-infected mice were similar and around the detection limit for both cytokines. IFNγ (C), IP-10 (D)and MIG (E) are increased both at 4 and 6 weeks after infection compared to non-infected mice. As MIG levels were higher in all infected mice than in all uninfected mice except 1, at 6 weeks significance was not reached (p = 0.08). Levels of MCP-1 (F) were increased in infected mice at 4 weeks post infection compared to uninfected mice. At both 4 and 6 weeks post infection the range of MCP-1 levels was quite wide between both infected and uninfected mice and levels at 6 weeks were very similar between infected and uninfected mice. * p<0.05, ** p<0.01, *** p<0.001