Table 2. Thermodynamic profiles of Alba1 binding to the calf thymus DNA and DNA oligonucleotides at 25°C and pH 7.0.
DNA | n | Kbin | ΔHbin | ΔSbin |
(106 M−1) | (cal/mol) | (cal/mol K) | ||
CT-DNA | 0.21±0.01 | 7.8±2.2 | −2849±112 | 22.0 |
A-DNA | 0.15±0.01 | 2.4±0.5 | −4477±167 | 14.2 |
B-DNA | 0.11±0.01 | 0.8±0.1 | −3112±492 | 17.9 |
n, binding site stoichiometry; Kbin, binding constant; ΔHbin, enthalpy change of binding; ΔSbin, entropy change.