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. 2013 Feb 28;8(2):e54016. doi: 10.1371/journal.pone.0054016

Figure 5. Effect of Lip-PLP on M1 and M2 marker expression within the synovium during AIA.

Figure 5

A: Expression of M1 markers. B: Expression of M2 markers. Mice were treated by intravenous injection of Lip-PLP or saline at day 3 after induction of the AIA and synovial biopsies were obtained at day 1 and day 5 after treatment. RE = Relative Expression compared to values of GAPDH. Data are expressed as mean +/− SD of eight animals. UD = undetectable. Statistical significance was determined by Student's t-test. * = P<0.05, ** = P<0.01 compared to saline treatment.