Table 2. Summary of the models presented in this analysis.

Model				Host	Regen.	Abs/CTL/IFN	Other cells
Bocharov [2]	13	49	19	Human	yes	Abs/CTL/IFN	Antigen-presenting macrophages, T and B helper cells, B cells, plasma cells, IFN-producing macrophages.
Baccam [4]	6	9	36	Human	no	IFN	—
Hancioglu [31]	10	28	0	Human	yes	Abs/CTL/IFN	Antigen-presenting macrophages, plasma cells.
Lee [22]	15	48	42	Mouse	yes	Abs/CTL	Dendritic cells, naive and effector CD4 T cells, naive CD8 T cells, naive and activated B cells, Long- and short-lived plasma cells.
Handel [6]	6	8	50	Mouse	yes	Abs/IFN	—
Miao [23]	6	8	64	Mouse	yes	Abs/CTL	—
Saenz [32]	8	12	96	Horse	no	IFN	—
Pawelek [37]	5	11	90	Horse	no	IFN	—

(number of variables), (number of parameters), (number of data points), Regen. (whether the model includes cell regeneration).

Model was not mathematically fit to data, but did have to conform to some general criteria.

We consider two different parameter sets for this model (Miao split and Miao full). The differences between these two models are described in Methods.

The Saenz and Pawelek models were fit to the same data.