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. 2013 Feb 28;8(2):e57088. doi: 10.1371/journal.pone.0057088

Table 4. Parameter values of the Miao split model using the Miao et al. model and data [23].

Description* Parameter Value
Infectivity of virions Inline graphic 2.5Inline graphic mL⋅Inline graphic⋅d−1
Target cell regeneration rate Inline graphic 1.2Inline graphic d−1
Death rate of infectious cells Inline graphic 0.47 d−1
Viral titer clearance rate Inline graphic 6.9 d−1
Viral production rate by infectious cells Inline graphic 100Inline graphic⋅mL−1⋅d−1 (fixed)
Initial number of susceptible cells Inline graphic 6.5Inline graphic
Initial virus concentration Inline graphic 1473Inline graphic⋅mL−1(fixed)
Killing rate of infectious cells by CTLs Inline graphic 5.6Inline graphic d−1
Removal rate of virions by IgG Abs Inline graphic 3.0Inline graphicmL⋅(pg⋅d)−1
Removal rate of virions by IgM Abs Inline graphic 6.5 mL⋅(pg⋅d)−1
*

See supplemental material S2 for a description of this model.