Table 2. Univariate and multivariate analysis for overall survival of 86 patients (analyze data of Notch1 expression).

Tumor characteristic	Relative risk (95% CI)	P-value
Univariate
Gender	0.664(0.407–1.083)	0.101
Age (years)	1.472(0.907–2.388)	0.118
Tumor location	0.852(0.525–1.383)	0.517
Tumor size	2.026(1.210–3.392)	0.007*
Tumor grade (differentiation)	0.712(0.427–1.188)	0.193
Metastasis	25.045(10.773–58.225)	<0.001*
Venous invasion	23.858(10.333–55.088)	<0.001*
Satellite lesions	1.587(0.938–2.684)	0.085
Tumor number	2.266(1.325–3.876)	0.003*
AJCC TNM stage	4.940(2.544–9.593)	<0.001*
AFP (ng/ml)	1.231(0.672–2.258)	0.501
Notch1	2.353(1.434–3.859)	0.001*
Multivariate
Tumor size	3.296(1.245–8.725)	0.016*
Metastasis	18.415(5.968–56.825)	<0.001*
Venous invasion	7.625(2.631–22.096)	<0.001*
Tumor number	2.790(1.522–5.116)	0.001*
AJCC TNM stage	1.034(0.313–3.418)	0.956
Notch1	1.787(1.012–3.155)	0.045*

95% CI: 95% confidence interval.

^*Statistically significant difference.