Table 3. Univariate and multivariate analysis for overall survival of 86 patients (analyze data of Notch3 expression).

Tumor characteristic	Relative risk (95% CI)	P-value
Univariate
Gender	0.856(0.531–1.379)	0.523
Age (years)	1.062(0.664–1.696)	0.802
Tumor location	0.996(0.624–1.590)	0.988
Tumor size	1.105(0.682–1.789)	0.686
Tumor grade (differentiation)	0.674(0.414–1.100)	0.114
Metastasis	8.965(4.845–16.590)	<0.001*
Venous invasion	18.410(8.600–39.407)	<0.001*
Satellite lesions	1.395(0.830–2.345)	0.209
Tumor number	1.352(0.798–2.289)	0.262
AJCC TNM stage	2.328(1.311–4.136)	0.004*
AFP (ng/ml)	0.925(0.522–1.639)	0.790
Notch3	2.848(1.743–4.654)	<0.001*
Multivariate
Metastasis	3.142(1.352–7.300)	0.008*
Venous invasion	8.774(3.143–24.492)	<0.001*
AJCC TNM stage	1.787(0.969–3.296)	0.063
Notch3	3.114(1.853–5.233)	<0.001*

95% CI: 95% confidence interval.

^*Statistically significant difference.